2021 Building Biology in 3D Hybrid Symposium
These recordings address the successes and limitations of using 3D systems in discovery and applied research, while acknowledging the need for improvements to ensure widespread adoption.
current and near-future enabling technologies,
applications of such systems in high-throughput screening,
advances in imaging and analysis of data generated
and the expansion into novel model systems.
Randy D. Blakely, Ph.D.
Executive Director, FAU Brain Institute, Professor of Biomedical Science, Charles E. Schmidt College of Medicine
Florida Atlantic University
Joern Dengjel, Ph.D
University of Friborg
Hongjun Song, Ph.D.
University of Pennsylvania
James Hoying, Ph.D.
Advanced Solutions Life Sciences
"James (Jay) Hoying is a leading expert in tissue vascularization, vascularized tissue models, and tissue model fabrication with more than 25 years of experience in basic and applied sciences involving tissue and vascular biology. Hoying is a founding Partner of Advanced Solutions Life Sciences and serves as its Chief Scientist. Previously, he was Professor and Chief of the Division of Cardiovascular Therapeutics at the Cardiovascular Innovation Institute (CII) where he developed a broad background in tissue fabrication, cell therapeutics, and translation of discoveries to industry and the clinic. He also has joint appointments at the Department of Physiology at the University of Louisville and the Department of Biotechnology at the University of New Hampshire. Hoying pioneered the use of native, intact microvascular elements in modeling vascularization and vascularizing tissues in vitro and in vivo. He holds numerous patents related to vascularizing tissues and related cell-based therapies. He has edited a book and published over 130 original research papers, reviews, and book chapters. As a researcher, he has secured nearly $18 million in grants as PI or co-PI. Hoying currently serves on the Editorial staff of Frontiers of Physiology and reviews for several other national and international journals. He reviews individual and program grant proposals for the National Institutes of Health, the Veterans Affairs, the American Heart Association, and international funding agencies. Hoying has organized, chaired and co-chaired more than 11 international and national conference sessions and delivered more than 51 keynote and invited talks at conferences and University seminars. He currently serves in an advisory role for 5 programs including the Leadership Advisory Council of the Advanced Regenerative Manufacturing Institute, the Research and Industry Council of the New Hampshire BioMade EPSCoR program, and the New Hampshire Tech Alliance/BioMed|Tech Leadership Council. He is also a Fellow of the American Heart Association. "
Daniel Todd, Ph.D.
Charles River Laboratories
Joseph Kissil, Ph.D.
Moffitt Cancer Center
Kristin Bircsaka, Ph.D.
Paul Johnston, Ph.D.
University of Pittsburgh Dept. Pharmaceutical Sci.
Dr. Johnston obtained a B.Sc. with Honors (2.1) (1978) and a Ph.D. (1983) in Biochemistry, from the University of East Anglia, Norwich, England. Postdoctoral positions at the University of North Carolina, Duke University, and the University of Texas Southwestern Howard Hughes Institute provided diverse experience in biochemistry, molecular biology, cell biology, immunology, protein purification and recombinant protein expression. Dr Johnston has twenty-nine years of drug discovery experience in the Pharmaceutical, Biotechnology, and Academic sectors. He is an innovator of cell based lead generation, and founding member of the Society for Biomolecular Imaging and Informatics. In 2005, he joined the University of Pittsburgh to design and build the Pittsburgh Molecular Library Screening Center where he led 21 HTS campaigns and the NCI 60 drug combination screen. In 2011, he established independent chemical biology laboratories to discover new drugs or drug combinations for prostate cancer, melanoma, and head and neck cancers.
Paul Kenny, Ph.D.
Mt. Sinai Icahn School of Medicine
Nikolay Samusik, Ph.D.
Sven Fengler, Ph.D.
German Center for Neurodegenerative Diseases
Andrew Aguirre, M.D., Ph.D.
Harvard Medical School
Carla Grandori, M.D., Ph.D.
SEngine Precision Medicine
James Hickman, Ph.D.
University of Central Florida NanoScience Technology Center
Pouria Rafsanjani Nejad
The University of Akron
David Tuveson, M.D., Ph.D.
Cold Spring Harbor Laboratory
Dr. Sirenko is an established cell biologist and imaging specialist who is an expert in developing assays with complex cell-based models for research and drug discovery. She is a senior scientist at Molecular Devices where she works on development of high-content imaging methods to the analysis of novel cell systems. Dr. Sirenko currently leads a group of scientists developing methods and new tools for automation of 3D cell models – including organoids and organ-on chips – for modeling cancer, neurotoxicity, and toxicology. Dr. Sirenko holds a PhD in Biochemistry/Biophysics, has over 15 years of industry experience, and has authored more than 35 scientific papers.